Pregabalin Lyrica Cas 148553-50-8

Pregabalin ,MF: C8H17NO2,MW: 159.23,CAS:148553-50-8

Pregabalin is a second- generation antiepileptic drug (AED) known with the proprietary brand name of Lyrica® (Pfizer, Tadworth) in the UK and USA (Pfizer, New York, NY).

Description

Pregabalin CAS 148553-50-8 Product Information

Product Name:Pregabalin
Synonyms:(S)-3-(Ammoniomethyl)-5-methylhexanoate;3(S)-(AMINOMETHYL)-5;LYRICA
CAS NO:148553-50-8
Molecular Weight:159.226
Molecular Formula:C8H17NO2
Boiling Point:274.0±23.0 °C at 760 mmHg
Melting point:194-196ºC
Density:1.0±0.1 g/cm3
Appearance:white powder
Applications:It is an anticonvulsant drug used for neuropathic pain, as an adjunct therapy for partial seizures, and in generalized anxiety disorder. It was designed as a more potent successor to gabapentin.It is marketed by Pfizer under the trade nam
Solubility:deionized water: ≥10mg/mL Soluble to 100 mM in water
Storage:2-8°C

pregabalin vs gabapentin

Pregabalin and gabapentin are both medications used to treat certain types of neuropathic pain and are also prescribed for other conditions. While they have some similarities, there are also important differences between the two drugs.

Pregabalin:

  • Pregabalin is sold under the brand name Lyrica.
  • It is approved by the FDA for the treatment of neuropathic pain associated with diabetic neuropathy, postherpetic neuralgia (nerve pain following shingles), fibromyalgia, and as an adjunctive therapy for partial-onset seizures in epilepsy.
  • Pregabalin is also sometimes prescribed off-label for anxiety disorders.
  • It has a more predictable absorption in the body and a higher bioavailability compared to gabapentin.
  • Pregabalin has a faster onset of action and may provide more consistent pain relief.

Gabapentin:

  • Gabapentin is sold under various brand names, including Neurontin and Gralise.
  • It is approved by the FDA for the treatment of postherpetic neuralgia, partial-onset seizures in epilepsy, and restless legs syndrome.
  • Gabapentin is also prescribed off-label for other conditions, such as neuropathic pain, migraines, and anxiety disorders.
  • It has a less predictable absorption in the body and lower bioavailability compared to pregabalin.
  • Gabapentin may require higher doses and more frequent dosing to achieve the desired effect.

Both pregabalin and gabapentin belong to a class of medications called gabapentinoids, and they work by reducing the release of certain neurotransmitters involved in pain signaling. They are generally well-tolerated but can cause side effects such as dizziness, drowsiness, and weight gain.

Pregabalin side effects

Common side effects of pregabalin may include dizziness, drowsiness, swelling in your hands and feet, trouble concentrating, increased appetite, weight gain, dry mouth, or blurred vision. If you experience any of these side effects or other unusual symptoms while taking pregabalin, it is important to contact your doctor immediately.

What is Pregabalin?

Pregabalin is a medication that is used to treat epilepsy, neuropathic pain, fibromyalgia, restless leg syndrome, opioid withdrawal and generalized anxiety disorder (GAD). It works by slowing down impulses in the brain that cause seizures and by reducing the release of certain neurotransmitters. I hope that helps.

Pregabalin uses

Pregabalin is used to treat epilepsy, neuropathic pain, fibromyalgia, restless leg syndrome, opioid withdrawal and generalized anxiety disorder (GAD). It is also used with other medications to treat partial onset seizures in adults and children aged at least 1 month. If you have any further questions or concerns about pregabalin, it is important to speak with your doctor or healthcare provider.

 

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