4-methylpropiophenone Cas 5337-93-9

4-methylpropiophenone cas 5337-93-9 is an aromatic ketone that is propiophenone bearing a methyl group at C-4. It derives from a propiophenone

4-methylpropiophenone Product Information:


Product Name:4′-Methylpropiophenone
CAS NO:5337-93-9
Molecular Weight:148.2
Molecular Formula:C10H12O
Boiling Point:238.5±0.0 °C at 760 mmHg
Melting point:7.2 °C
Density:1.0±0.1 g/cm3
Appearance:Colourless Oil
Applications: 4′-Methylpropiophenone can be used as a building block to synthesize:
N-(4-Chlorophenyl)-N′-[1-(4-methylphenyl)propyl]urea as a potential CRAC channel inhibitor.
Mono and trinuclear cobaloxime/organocobaloxime complexes, which are used as efficient catalysts for the synthesis of cyclic carbonates.
Solubility:Soluble in chloroform and hexane.
Storage:Inert atmosphere, Room Temperature

4′-Methylpropiophenone Uses

4-Methylpropiophenone is a chemical reagent with an aromatic ketone that is propiophenone bearing a methyl group at C-4. It serves as pharmaceutical and synthesis material intermediate, and it is also used in electrocarboxylation reactions.

4′-Methylpropiophenone, also known as p-Tolyl methyl ketone or 4-Methylphenylacetone, has various uses in different industries. Here are some common applications:

  1. Pharmaceutical Intermediates: 4′-Methylpropiophenone is often used as an intermediate in the synthesis of pharmaceutical compounds. It serves as a building block in the production of drugs and pharmaceutical ingredients.
  2. Fragrance and Flavor Industry: Due to its aromatic properties, 4′-Methylpropiophenone is utilized in the fragrance and flavor industry. It contributes to the creation of scents and flavors in products such as perfumes, colognes, soaps, and food additives.
  3. Chemical Research and Development: Researchers and chemists may employ 4′-Methylpropiophenone as a starting material or reagent in the development of new chemical compounds. It provides the necessary structural elements for the synthesis of various organic molecules.
  4. Organic Synthesis: 4′-Methylpropiophenone finds applications in diverse organic synthesis reactions. It can be used to produce other ketones, alcohols, and carboxylic acids through further chemical transformations.
  5. Laboratory Reagent: In laboratory settings, 4′-Methylpropiophenone may serve as a reagent or reference compound for analytical purposes, characterization studies, or experimental procedures.
  6. 4 Methylpropiophenone Reddit

From Reddit user said that this is start to finish, shows how to get to the 4 methylpropiophenone.

4 Methylpropiophenone Synthesis

To synthesize 4-methylpropiophenone, mix acetophenone and isobutyraldehyde in a 1:1 ratio with an acid catalyst. Add a solvent and heat the mixture under reflux conditions for 4-6 hours. After cooling, extract the crude product with water, separate the organic layer, and dry it with drying agents. Optionally, purify the product through simple distillation.

4-methylpropiophenone uses

4-Methylpropiophenone is a chemical reagent used in electrocarboxylation reactions. It is as a raw material for organic synthesis of agrochemicals, pharmaceuticals and dyestuff.

4-methylpropiophenone synthesis

4-Methylpropiophenone is prepared via Friedel Craft reaction for Toluene and propionyl chloride, in the presence of Aluminium Chloride as a catalyst.

4-methylpropiophenone msds




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SKU CAS-5337-93-9Categories Buy directly, Organic reagentsTags 2 bromo 4 methylpropiophenone, 4 methylpropiophenone, 4 methylpropiophenone synthesis, 5337-93-9


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